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Biogen Idec, Isis in Global Antisense Program

Pact to target spinal muscular atrophy

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By: Tim Wright

Editor-in-Chief, Contract Pharma

Biogen Idec and Isis Pharmaceuticals have entered into an exclusive, worldwide option and collaboration under which the companies will develop and commercialize Isis’ antisense investigational drug, ISIS-SMNRx, for the treatment of spinal muscular atrophy (SMA). SMA is a genetic neuromuscular disease characterized by muscle atrophy and weakness, and it is the most common genetic cause of infant mortality. Isis’ ISIS-SMNRx is designed to compensate for the underlying genetic defect that causes SM...

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